BioGenex provides a “Total Solution” for slide-based cell and tissue analysis to accelerate clinical diagnostics and drug discovery development. We have developed the total walk-away, industrial-scale automated systems to streamline and standardize an array of processes for cell and tissue testing in immunohistochemistry (IHC), in situ hybridization (ISH), Fluorescent in situ hybridization (FISH), special stains.
Our products include more than 400 antibodies (monoclonal and polyclonal) for various cancer panels, highly sensitive detection kits, automated systems, mRNA, miRNA, and FISH probes, ancillary reagents, and consumables. We accommodate diverse laboratory needs with an array of clinical and research automation platforms that meet global quality standards (ISO 13485 & ISO 9001), are approved by the FDA and CE-marked. BioGenex is a global market leader in molecular pathology providing customer-centric solutions for complete automation of cell and tissue staining. Through its cutting-edge and patented technologies, the company has transformed the practice of slide-based staining in many molecular pathology laboratories.
Fluorescent in situ hybridization (FISH)
Fluorescent in situ hybridization has become a well-known method for genetic mapping and gene expression profiling. This technique exploits the use of fluorescent dye-labeled probes against a nucleotide sequence of DNA that is mapped or localized to a chromosome or intra-nuclear DNA to generate a fluorescence signal which in turn is visualized in situ by microscopy. The hybridization of the probe to the corresponding nucleotide sequence enables detection of the presence or absence of specific sequences, mapping of translocation
As a diagnostic tool, FISH is widely used in clinical genetics, neuroscience, reproductive medicine, toxicology, microbial ecology, evolutionary biology, comparative genomics, cellular genomics